The symptoms of an Alpha-1 MZ individual are related to a ~50% lower level of alpha-1 antitrypsin in the body, and the fact that 50% of the alpha-1 antitrypsin gets “stuck” in the liver, which induces liver- and digestive issues.
Within the Alpha-1 MZ group, we’ve started a correlation study to get a better idea of the most common health issues/symptoms (please note: since lung issues are well known, these were not part of this study).
This study will be expanded to a large group in the near future.
Prevailing health conditions within the small group of MZ’s:
- B12 deficiency, leading to different types of neuropathy
- Vitamin D25 deficiency
- Iron deficiency (some on infusions)
- Intermittent pain in the liver area
- Light color stool, bloating and flatulence
- Only easy to digest food is accepted
- Issues keeping the body warm
- Low glucose levels
- High blood pressure
- Pain in joints (connective tissues and arthritis)
- Unable to deal with medications like NSAIDs and/or other medication
- More illness during childhood with lung related issues
- In need of more salt intake was also mentioned (needs further investigation)
- Reduced immune response, including deficiency of thrombocytes / lymphocytes
- Skin issues like eczema or psoriasis
- Lung related issues, like lung emphysema and bronchiectasis
- Liver related issues, fatty liver, liver Fibrosis, cirrhosis
- Connective tissue related issues, like tendon, tendon sheaths and ligaments
- Immune problems, like autoimmune and immune response issues
- Anti-inflammatory issues
- Digestive issues causing:
- B12 / neurological problems
- Calcium absorption issues and low vitamine D status
- Iron deficiency
- Digestive / absorption issues in the small intestine, which causes various vitamin and minerals deficiency issues.