Medical Research & Publications
Welcome to Alpha 1 MZ Medical Research & Publications section.
Here, you will find abstracts with references to Alpha 1 MZ related publications with a focus on the PiMZ liver and the induced issues.
We also like to take this opportunity to thank all medical institutions, pharmaceuticals and researchers for their continues effort in understanding all the bio chemical effects of a PiMZ liver and making these pubilications available.
List of medical literature with links to abstracts and papers
Section 1 (Liver related)
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The Recruitment-Secretory Block (“R-SB”) Phenomenon and Endoplasmic Reticulum Storage Diseases.
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Diploid hepatocytes drive physiological liver renewal in adult humans.
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Aging and liver disease. David A. Brenner
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Why do some Alpha's develop liver disease and others not.
Section 2 (Immune related)
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Why do some adults with PiMZ Alpha 1 antitrypsin develop bronchiectasis
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Immune-modulating effects of Alpha 1 antitrypsin
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The Role of Neutrophils in Alpha-1 Antitrypsin Deficiency
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Alpha-1 Antitrypsin Therapy for Autoimmune Disorders
Section 3 (Biliary Tract)
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Genome-wide association meta-analysis yields 20 loci associated with gallstone disease
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Pleiotropic associations of heterozygosityfor the SERPINA1 Z allele
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Increased Prevalence of Alpha-1-Antitrypsin Deficiency in Patients with Biliary Tract Cancer and Its Associated Clinicopathological Features
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Bile duct adenomas in heterozygous (MZ) deficiency of alpha 1-protease inhibitor
Section 4
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Bile acids as modulators of gut microbiota composition and function
- Aneurysmal Disease / Connective Tissue
- Alpha 1 antitrypsin deficiency alleles are associated with joint dislocation and scoliosis in Williams syndrome
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